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DITERPENE FURANOIDS COMPOUND FOR INHIBITING A PROTEIN TYROSINE DEPHOSPHORYLATION ENZYME 1B WHICH CAN BE USED IN THE TREATMENT AND PREVENTION OF DIABETES, AND THE USE THEREOF
DITERPENE FURANOIDS COMPOUND FOR INHIBITING A PROTEIN TYROSINE DEPHOSPHORYLATION ENZYME 1B WHICH CAN BE USED IN THE TREATMENT AND PREVENTION OF DIABETES, AND THE USE THEREOF
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机译:用于抑制蛋白酪氨酸去磷酸化酶1B的二萜呋喃类化合物,可用于治疗和预防糖尿病及其用途
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摘要
PURPOSE: A diterpene furanoids compound inhibiting a protein tyrosine dephosphorylation enzyme 1B, and the use thereof are provided to have an excellent effect of medical treatment on insulin-independent type-2 diabetes.;CONSTITUTION: A Huea coralligera extract has an activity inhibition of a protein tyrosine dephosphorylation enzyme 1B(PTP1B). The Huea coralligera extract is extracted with a solvent selected from the group of water, lower alcohol with 1-4 carbons, and a mixture thereof. The diterpene furanoids compound is represented by chemical formula 1-4. A separation method of a Hueafuranoids compound is represented by the chemical formula 1 or the chemical formula 2. A pharmaceutical composition for the treatment of type-2 diabetes contains the Huea coralligera extract as an active ingredient.;COPYRIGHT KIPO 2013
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