COMPOSITION COMPRISING LACTOBACILLUS PLANTARUM DSR CK10 OR LACTOBACILLUS PLANTARUM DSR M2 AS AN EFFECTIVE INGREDIENT FOR TREATMENT OF INFLAMMATORY DISEASES

摘要

PURPOSE: A composition containing Lactobacillus plantarum DSR CK10 or Lactobacillus plantarum DSR M2 for treating inflammatory diseases is provided to suppress the expression of one or more cytokines among TNF-alpha, IL-6, and MCP-1, and to suppress NO generation. CONSTITUTION: A pharmaceutical composition for treating cancer or inflammatory diseases contains Lactobacillus plantarum DSR CK10 or Lactobacillus plantarum DSR M2 as an active ingredient. The pharmaceutical composition suppresses cytokine expression or NO generation. The inflammatory diseases are selected from arthritis, rheumatoid arthritis, polymyalgia rheumatica, inflammatory bowel disease, ulcerative colitis, Crohn disease, encephalomyelitis, meningitis, pancreatitis, peritonitis, osteomyelitis, encephalitis, meningitis, rhinitis, and acute bronchitis. A food composition for preventing and treating inflammatory diseases or cancer contains Lactobacillus plantarum DSR CK10 or Lactobacillus plantarum DSR M2 as an active ingredient. [Reference numerals] (AA) Treat with LPS 0.5ug/ml for 4h after treat a specimen for 24h