RABBIT MODEL EXHIBITING VASCULAR CALCIFICATION INDUCED BY INFLAMMATION

摘要

PURPOSE: A rabbit model exhibiting vascular calcification induced by inflammation is provided to be useful for the pathogenesis of the vascular calcification and studies for diseases related to the vascular calcification. CONSTITUTION: A rabbit model exhibits vascular calcification by periodically administering an inflammation inducing material into a normal rabbit. The inflammation inducing material is carrageenan or lipopolysaccharide. The carrageenan is selected from a group including L-carrageenan, K-carrageenan, and lambda-carrageenan.