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Method for preparing rabbit model exhibiting advanced atherosclerosis by cholesterol-supplemented diet and inflammation
Method for preparing rabbit model exhibiting advanced atherosclerosis by cholesterol-supplemented diet and inflammation
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机译:补充胆固醇饮食和发炎的晚期动脉粥样硬化兔模型的制备方法
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摘要
PURPOSE: A rabbit model for exhibiting advanced atherosclerosis is provided to have similar characteristics to advanced atherosclerosis and to be easily conducted within a short term. CONSTITUTION: A rabbit model exhibiting advanced atherosclerosis includes an advanced atherosclerosis induced by cholesterol-supplemented diet and inflammation by periodically injecting an inflammation-inducing material to a rabbit with cholesterol-supplemented diet. The cholesterol-supplemented diet is conducted by feeding the rabbit feed with 0.5-1.5 wt% of cholesterol. The inflammation-inducing material is carrageenan or lipopolysaccharide.
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