COMPOSITION CONTAINING A NATURAL PIGMENT OF LITHOSPERMUM ERYTHRORHIZON SIEB. ET ZUCC. ROOTS FOR PREVENTING AND TREATING OSTEOARTHRITIS AND A METHOD FOR PREPARING THE SAME

摘要

PURPOSE: A composition containing a Lithospermum erythrorhizon Sieb. et Zucc. root extract is provided to significantly treat osteoarthritis and to be used as an agent for preventing and treating osteoarthritis or as a health food for treating osteoarthritis.;CONSTITUTION: A therapeutic agent for treating osteoarthritis contains effective amount of natural pigments of Lithospermum erythrorhizon Sieb. et Zucc. roots. The natural pigment is a shikonin derivative, acetyl shikonin. An agent for preventing osteoarthritis contains effective amount of the natural pigments. A method for preparing a Lithospermum erythrorhizon Sieb. et Zucc. root extract for preventing and treating osteoarthritis comprises the steps of extracting Lithospermum erythrorhizon Sieb. et Zucc. roots with a non-polar solvent and obtaining the natural pigments. A method for preparing a Lithospermum erythrorhizon Sieb. et Zucc. root extract for preventing and treating osteoarthritis comprises the step of extracting the natural pigments by supercritical extraction.;COPYRIGHT KIPO 2013;[Reference numerals] (G2) MIA + green-shelled mussel oil extract 150mg/kg; (G3) MIA + supercritical extract of Lithospermum erythrorhizon Sieb. et Zucc. 200mg/kg; (G4) MIA + acetylshikonin of Lithospermum erythrorhizon Sieb. et Zucc. 5mg/kg