R12 - GRIM19 FUSION PEPTIDE HAVING CELL PENETRATION FOR PREVENTING OR TREATING IMMUNE DISEASE AND PHARMACEUTICAL COMPOSITION COMPRISING THEREOF

摘要

PURPOSE: R12-Grim19 fusion peptide is provided to be usefully used as an immune suppressant or a pharmaceutical composition which prevents or treats immune disease including autoimmune disease due to the modulation of an immune reaction, inflammation disease and transplantation rejection disease. CONSTITUTION: Recombinant peptide in which twelve successive arginene (R) and Grim19 are fused is provided. The recombinant peptide has an amino acid sequence represented by a sequence number 1. A vector includes a base sequence coding the peptide. The base sequence comprises a base sequence represented by a sequence number 2. A composition for prevention or treatment of the immune disease includes the peptide.