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METHOD FOR INACTIVATING PROTEASES BY PH CHANGE IN A LIQUID OBTAINED FROM A CELL CULTURE
METHOD FOR INACTIVATING PROTEASES BY PH CHANGE IN A LIQUID OBTAINED FROM A CELL CULTURE
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机译:通过从细胞培养液中获得的pH值变化来灭活蛋白酶的方法
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摘要
The invention relates to a process for inactivating proteases by repeatedly changing the pH in the cell culture supernatant at the start of the process for the purification of biopharmaceuticals. The pH is adjusted first to 3-5, and then to 7-9.
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