首页> 外国专利> Localized surface plasmon resonance sensor of gold nonorod with improving sensitivity, method of preparing the same and method of detecting bioproduct using the same

Localized surface plasmon resonance sensor of gold nonorod with improving sensitivity, method of preparing the same and method of detecting bioproduct using the same

机译:具有提高的灵敏度的非金金局部表面等离子体激元共振传感器,其制备方法和使用该传感器的生物制品检测方法

摘要

The invention nano by modifying the aspect ratio of the gold nanorods, optimize the size and gold nanorod surface and downsized to a level, and the detection limit due to the reduced steric hindrance excellent, excellent sensitivity relates to the localized surface plasmon resonance sensor and a method of gold nano-rods having the gold nano-rods and which is formed on the surface of the gold nano-rods comprises a self-assembled monolayer, and wherein the self-assembled monolayer is a terminal thiol group, a carboxyl group and a hydroxyl group that is formed by an organic absorbent which is bonded to the feature, and localized surface plasmon of the gold nano-rods of the present invention resonance sensor is the optimized aspect ratio, has a physical property such as size, as by the gold nano-rods, and modifying the surface of an organic absorbent, enabling a reduction in the size of a nano-scale in the sensor size, and the steric hindrance in the detection sensitivity reduction can lead to a significant improvement of the detection limit. Thus, the detection of complex mixtures, the early detection of cancer, infections, and the gold nano-rods sensor according to the invention in the early prevention of neurological disorders such as may be utilized in various ways. ;
机译:本发明通过改变金纳米棒的长径比,优化金纳米棒的尺寸和表面尺寸并将其缩小到一定水平,并且由于降低了空间位阻而获得的检测极限极好,灵敏度与局部表面等离子体激元共振传感器有关。具有金纳米棒并且形成在金纳米棒的表面上的金纳米棒的方法包括自组装单层,并且其中该自组装单层是末端硫醇基,羧基和由结合到特征上的有机吸收剂形成的羟基和本发明的金纳米棒的局部表面等离子体激元是优化的纵横比,具有诸如金的物理性质,例如尺寸纳米棒,并修饰有机吸收剂的表面,从而可以减小传感器尺寸的纳米级尺寸,并且可以减轻检测灵敏度的空间障碍d大大提高了检出限。因此,可以以各种方式利用复杂混合物的检测,癌症,感染的早期检测以及根据本发明的金纳米棒传感器在神经疾病的早期预防中。 ;

著录项

  • 公开/公告号KR101222893B1

    专利类型

  • 公开/公告日2013-01-17

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20110062791

  • 发明设计人 심상준;

    申请日2011-06-28

  • 分类号G01N33/48;G01N33/574;G01N21/25;

  • 国家 KR

  • 入库时间 2022-08-21 16:25:51

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