Phthalazinone derivatives substituted 5-membered heterocyclic aryl, or pharmaceutically acceptable salts thereof, preparation method therof and pharmaceutical composition

摘要

5- ring heteroaryl substituted by Tala profile Xenon derivatives, their preparation , and it includes , as an active ingredient, which provides a pharmaceutical composition . Xenon by phthalazine derivatives substituted 5- ring heteroaryl group according to the invention act as antagonists for MCH ( melanin concentrating hormone ) receptor is induced by obesity MCH binding to the MCH receptor-1 , diabetes , metabolic disorders , anxiety and can be used , such as depression and related disorders MCH receptor-1 is useful for preventing or treating .