Positively charged superparamagnetic iron oxide nanoparticles, contrast agent using the same and method for preparation thereof

摘要

positive polarity superparamagnetic iron oxide nanoparticle contrast agents using the same and provide a method for manufacturing the same The . Positive polarity superparamagnetic iron oxide nanoparticles comprises a cationic material attached to the polymer layer , and an amide bond on the surface of the polymer layer comprises a polymer containing superparamagnetic iron oxide nanoparticles , a large number of carboxyl groups which is coated on the surface of the nanoparticles The . According to the invention, the magnetic iron oxide to have a portrait , yet simple , yet strong cationic hydrophilic nanoparticles can be produced with high reproducibility . Positive polarity superparamagnetic iron oxide nanoparticles prepared has a high intracellular absorption efficiency and reliability , can be utilized in various ways as an effective contrast agent with a non-invasive living body image . ;