Novel use of sodium-dependent inorganic phosphate transporter-2b gene

摘要

PURPOSE: An inhibitor of sodium-dependent inorganic phosphate transporter-2b gene or protein expressed from the gene and a composition for treating cancer containing the same are provided to suppress generation and growth of cancer. CONSTITUTION: An inhibitor of sodium-dependent inorganic phosphate transporter-2b gene is siRNA(small interfering RNA) or shRNA(small hairpin RNA) of sodium-dependent inorganic phosphate transporter-2b gene. A composition for treating cancer contains the inhibitor of sodium-dependent inorganic phosphate transporter-2b gene. The inhibitor suppresses AKT activation. A composition for screening anticancer drug contains the sodium-dependent inorganic phosphate transporter-2b gene or protein expressed from the gene.