MULTI-LAYER ABSORBABLE BARRIER MEMBRANES FOR GUIDING BONE TISSUE REGENERATION

摘要

PURPOSE: A multi-layer absorbent periodontal tissue regeneration inducing film is provided to efficiently block the infiltration of soft tissue with a constant stiffness and to protect a space sufficiently until being divided into bone tissues without any separate physical method or medicine treatment. CONSTITUTION: A multi-layer absorbent periodontal tissue regeneration inducing film includes a bioabsorbable shielding membrane which is composed of a biodegradable material and a composite shielding membrane combined with PEG(PolyEthylene Glycol) originated aquagel(hydrogel). The surface of the biodegradable material can be provided with a layer structure in which the aquagel is coated. A layer structure coated with the hydrogel is formed on the surface of the biodegradable material. The hydrogel includes PEG having a photopolymerizable functional group, photopolymeraization initiator capable of forming radical for the initiation of the photopolymerization of the PEG, and a natural polymer additive with a biodegradable speed faster than the photopolymerized PEG in order to form the photopolymerized PEG and the IPN(Interpenetrating Polymer Network). [Reference numerals] (AA) Amount of a shielding membrane remaining in tissue extracted when 12 weeks passed after implanting the shielding membrane in SD-rat; (BB) Single-layer absorbent shielding membrane; (CC) Double-layer absorbent shielding membrane