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Biomarker for diagnosing obesity or obesity related diseases, and composition for treating or preventing obesity or obesity related diseases

机译:用于诊断肥胖或与肥胖相关的疾病的生物标志物,以及用于治疗或预防肥胖或与肥胖相关的疾病的组合物

摘要

The present invention comprises a fatty acid represents a specific expression patterns in specific serum sex, obesity or obesity related disease diagnostic biomarkers and relates to the treatment or prevention of obesity or obesity related diseases for the composition , the fatty acids are in particular contained in a female -specific serum FAT / CD36 gene expression by promoting the differentiation of adipocytes in skeletal muscle stem cells Since induction , can be diagnosed obesity or obesity -related diseases by evaluating the expression and secretion levels of these fatty acids . In addition, these specific fatty acids can be developed to effectively treat obesity or obesity -related diseases through or improvement of synthesis inhibitor . ;
机译:本发明包含代表特定血清性别,肥胖或肥胖相关疾病诊断生物标志物的特定表达模式的脂肪酸,并且涉及组合物的肥胖或肥胖相关疾病的治疗或预防,所述脂肪酸特别包含在女性特定的血清FAT / CD36基因表达通过促进骨骼肌干细胞中脂肪细胞的分化诱导而产生,通过评估这些脂肪酸的表达和分泌水平,可以诊断出肥胖或肥胖相关疾病。此外,这些特定的脂肪酸可以通过合成抑制剂的开发或改进来开发,以有效治疗肥胖或与肥胖相关的疾病。 ;

著录项

  • 公开/公告号KR101284521B1

    专利类型

  • 公开/公告日2013-07-16

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20100026478

  • 发明设计人 이은주;최인호;이동목;신유미;

    申请日2010-03-24

  • 分类号G01N33/92;A61K39/395;G01N33/15;A61P3/04;

  • 国家 KR

  • 入库时间 2022-08-21 16:24:53

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