Corynebacterium sp. Having Improved L-ornithin Production and Process for Preparing the L-ornithin Employing the Same

摘要

The invention L- ornithine producing microorganism of the genus Corynebacterium ability improved by it and L- ornithine relates to the manufacturing method of tin, the present invention more specifically, the intrinsic activity of the glucose dehydrogenase (GDH) is reduced or inactivated, L- ornithine producing ability improved microorganism of the genus Corynebacterium, the production of the microorganism A method and cultured using glucose as a carbon source for the microorganism, and will L- ornithine from the culture relates to a process for the preparation of L- ornithine comprises recovering the tin. By using the microorganism of the genus Corynebacterium in a reduced intrinsic activity of glucose dehydrogenase enzymes of the present invention, the pentose phosphorylation, as well as the path is activated, the specific activity of the enzyme, G6PDH and 6PGD involved in pentose phosphorylation path NADPH production yield is increased due to the increase and, therefore, can improve the production yield of L- ornithine with the NADPH, L- ornithine efficient and may be utilized widely for economical production. ;