EFFECTS OF ORAL COMPOSITION AGAINST LOSS OF BONE MASS AND LOSS OF ATTACHMENT

摘要

1. A method for identifying a compound suitable for treating a disease or condition of the oral cavity, comprising: obtaining a first gingival sample from a mammal suffering from a disease or condition of the oral cavity; obtaining a second gingival sample from the oral cavity of the aforementioned mammal; reacting the above first sample with a test compound; the interaction of the above second sample with a positive control, in which the above positive control is a a unity known to suppress the expression of one or more matrix metalloproteinases; measuring the degree to which the expression of one or more of the above matrix metalloproteinases is inhibited by the above test compound; measuring the degree to which the expression of one or more of the above matrix metalloproteinases is suppressed by the above positive control; a comparison of the degree to which the expression of one or more of the above matrix metalloproteinases is inhibited by the above test compound, with the degree to which the expression of one or more of the above matrix metalloproteinases is suppressed by the above positive control; in which the test compound that inhibits the expression of one or more of the above matrix metalloproteinases to an equal or greater degree than the above positive control is connected suitable for the treatment of a disease or condition of the oral cavity. 2. The method according to claim 1, in which the above one or more