首页> 外国专利> The use of monomeric iodine-containing contrast agents in high dosages for x-ray diagnostics, in particular for invasive x-ray diagnostics and radiation therapy, enhanced iodine-containing

The use of monomeric iodine-containing contrast agents in high dosages for x-ray diagnostics, in particular for invasive x-ray diagnostics and radiation therapy, enhanced iodine-containing

机译:高剂量含碘单体造影剂在X射线诊断,特别是有创X射线诊断和放射治疗中的应用,增强了含碘

摘要

1. Diagnostic or therapeutic composition containing a monomeric iodine-containing radiopaque substance for X-ray-supported diagnostics or therapy for the use of a contrast agent in a high dose. A diagnostic or therapeutic composition containing a monomeric iodine-containing radiopaque substance, backed up by an X-ray diagnostic or therapy for the use of a high dose contrast medium for patients with limited renal function or renal failure. 3. A diagnostic or therapeutic composition containing a monomeric iodine-containing radiopaque substance for X-ray-supported diagnostics or therapy for the use of a high-dose contrast agent for the prevention of nephropathy. 4. A diagnostic or therapeutic composition according to claims 1, 2, or 3, wherein the radiopaque substance is selected from the group consisting of iopromide, iohexol, omeprol and iopamidol. 5. A diagnostic or therapeutic composition according to claim 4, wherein the radiopaque substance is iopromide. A method of x-ray-supported diagnostics or therapy using a high-dose radiopaque substance, wherein the composition according to claims 1-5.7 is used. The method according to claim 6, wherein iopromide is used as a radiopaque substance and a dose of from 0.6 g of iodine / kg to 2 g of iodine / kg is used. The method according to claim 6, wherein a dose of from 1 g of iodine / kg to 7 g of iodine / kg is used. A method of obtaining a diagnostic or therapeutic composition for x-ray-supported diagnostics or therapy for the use of a high-dose X-ray substance with
机译:1.用于高剂量使用造影剂的用于X射线支持的诊断或治疗的诊断或治疗组合物,其包含含碘的不透射线单体。一种诊断或治疗组合物,其包含含单体碘的不透射线物质,并通过X射线诊断或治疗作为后盾,以供高剂量造影剂用于肾功能有限或肾衰竭的患者。 3.一种诊断或治疗组合物,其包含用于X射线支持的诊断或疗法的含单体的含碘不透射线的物质,用于使用大剂量造影剂预防肾病。 4.根据权利要求1、2或3的诊断或治疗组合物,其中所述不透射线的物质选自碘普罗米特,碘海醇,奥美普尔和碘帕醇。 5.根据权利要求4的诊断或治疗组合物,其中所述不透射线的物质是碘普罗胺。一种使用高剂量不透射线物质进行X射线支持的诊断或治疗的方法,其中使用了权利要求1-5.7的组合物。 7.根据权利要求6所述的方法,其中使用碘普罗胺作为不透射线的物质,并且使用0.6g碘/ kg至2g碘/ kg的剂量。 7.根据权利要求6的方法,其中使用1g碘/ kg至7g碘/ kg的剂量。一种获得诊断或治疗组合物的方法,所述诊断或治疗组合物用于使用高剂量X射线物质的X射线辅助的诊断或治疗,

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