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APPLICATION OF THE COMBINATION OF TERIFLUNOMIDE AND INTERFERON BETA FOR THE TREATMENT OF MULTIPLE SCLEROSIS

机译:特氟苯胺和干扰素β联合治疗多发性硬化症的应用

摘要

1. A method of treating a relapsing-remitting form of multiple sclerosis in a patient in need thereof, comprising administering to the patient approximately 7 mg or approximately 14 mg of teriflunomide and a pharmaceutically effective amount of interferon beta-1a or -1b.2. The method of claim 1, comprising administering to the patient approximately 7 mg or approximately 14 mg of teriflunomide once a day and a stable dose of interferon beta-1a or -1b. 3. An effective clinical trial method for treating a relapsing-remitting form of multiple sclerosis in a patient in need thereof, comprising administering to the patient approximately 7 mg or approximately 14 mg of teriflunomide once a day and a stable dose of interferon beta-1a or -1b.4. A method for reducing the number of T1-Gd foci in a patient suffering from a relapsing-remitting form of multiple sclerosis, comprising administering to the patient about 7 mg or about 14 mg of teriflunomide and a pharmaceutically effective amount of interferon beta-1a or -1b.5. The method according to claim 4, comprising administering to the patient approximately 7 mg or approximately 14 mg of teriflunomide once a day and a stable dose of interferon beta-1a or -1b. An effective, clinically proven method for reducing the number of T1-Gd foci in a patient suffering from a relapsing-remitting form of multiple sclerosis, comprising administering to the patient approximately 7 mg or approximately 14 mg of teriflunomide once a day and a stable dose of interferon beta-1a or -1b. 7. A method for reducing the number of T1-Gd foci in a patient suffering from a relapsing-remitting form of multiple sclerosis, comprising administering to the patient approximately
机译:1.一种在有需要的患者中治疗复发-缓解形式的多发性硬化的方法,其包括向所述患者施用约7mg或约14mg的特立氟胺和药学有效量的干扰素β-1a或-1b.2。 。 2.根据权利要求1所述的方法,其包括每天向所述患者施用约7mg或约14mg的特立氟胺和稳定剂量的干扰素β-1a或-1b。 3.一种用于在有需要的患者中治疗复发-缓解形式的多发性硬化的有效临床试验方法,包括每天向患者施用约7mg或约14mg的特立氟胺和稳定剂量的干扰素β-1a。或-1b.4。一种减少患有复发-缓解型多发性硬化症的患者中T1-Gd病灶数量的方法,该方法包括向该患者给药约7 mg或约14 mg的特立氟胺和药学有效量的干扰素β-1a或-1b.5。 5.根据权利要求4所述的方法,其包括每天给予所述患者约7mg或约14mg的特立氟胺和稳定剂量的干扰素β-1a或-1b。一种有效的,临床证明有效的方法,可减少患有复发-复发型多发性硬化症的患者中的T1-Gd病灶数量,包括每天给患者服用约7 mg或约14 mg的teriflunomide和稳定剂量β-1a或-1b干扰素。 7.一种用于减少患有复发-缓解形式的多发性硬化症的患者中的T1-Gd病灶数量的方法,其包括向所述患者施用约

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