首页> 外国专利> RTN-CONTAINING THERAPEUTIC / PREVENTIVE AGENT AGAINST OSTEOPOROSIS, CHARACTERIZED THAT RTN IS ADDED ONCE ONCE A WEEK IN THE STANDARD DOSE OF 100-200 UNITS

RTN-CONTAINING THERAPEUTIC / PREVENTIVE AGENT AGAINST OSTEOPOROSIS, CHARACTERIZED THAT RTN IS ADDED ONCE ONCE A WEEK IN THE STANDARD DOSE OF 100-200 UNITS

机译:含有RTN的抗骨质疏松症/预防剂,其特征在于,一旦在标准剂量下100-200单位一周就添加了RTN

摘要

1. An agent for treating or preventing osteoporosis that contains PTH as an active ingredient, characterized in that it is used together with a calcium-containing agent, and PTH is administered once a week in a standard dose of 100-200 units. An agent for treating or preventing osteoporosis according to claim 1, characterized in that the calcium-containing agent used in combination is administered once or several times a week. An agent for treating or preventing osteoporosis according to claim 1 or 2, characterized in that the calcium-containing agent used in combination is administered at a dose of 200-800 mg / day in the form of calcium. An agent for treating or preventing osteoporosis according to claim 1 or 2, wherein said PTH is human PTH (1-34) .5. An agent for treating or preventing osteoporosis according to claim 1 or 2 for administration over a period exceeding 24 weeks or 48 weeks. An agent for treating or preventing osteoporosis according to claim 1 or 2 for treating patients with osteoporosis who satisfy all of the following conditions 1-3 below: (1) Age 65 years or more, (2) Predominant bone fractures, (3) Bone density less than 80% of the average density of a young adult and / or a degree of bone atrophy I or higher. 7. An agent for treating or preventing osteoporosis according to claim 1 or 2 for treating or preventing secondary osteoporosis caused by a glucocorticoid or diabetic osteoporosis. An agent for treating or preventing osteoporosis according to claim 1 or 2 for treating or preventing osteoporosis in patients having at least one of the diseases (1) to (8) below as a complication: (1) Diabetes, (2) Hypertension, ( 3) Hyperlipidemia, (4) Arthralgia, (5) Osteoarthritis of the spine, (6)
机译:1.一种以PTH为有效成分的骨质疏松症的治疗或预防剂,其特征在于,其与含钙剂一起使用,PTH以100〜200单位的标准剂量每周给药一次。 2.根据权利要求1所述的骨质疏松症的治疗剂,其特征在于,组合使用的含钙剂每周一次或数次给药。 3.根据权利要求1或2所述的骨质疏松症的治疗剂,其特征在于,组合使用的含钙剂以200〜800mg /天的剂量以钙的形式给药。 3.根据权利要求1或2所述的骨质疏松症的治疗或预防剂,其中,所述PTH为人PTH(1-34).5。 3.根据权利要求1或2所述的骨质疏松症的治疗或预防药,其给药时间超过24周或48周。 3.根据权利要求1或2所述的骨质疏松症的治疗剂或预防剂,该骨质疏松症的治疗者满足以下1-3的所有以下条件:(1)年龄65岁以上,(2)主要的骨折,(3)骨密度小于年轻人的平均密度的80%和/或骨萎缩程度I或更高。 7.根据权利要求1或2的治疗或预防骨质疏松症的药物,用于治疗或预防由糖皮质激素或糖尿病性骨质疏松症引起的继发性骨质疏松症。 3.根据权利要求1或2所述的骨质疏松症的治疗或预防药,其用于治疗以下疾病(1)〜(8)中的至少一种并发的患者:(1)糖尿病,(2)高血压,( 3)高脂血症,(4)关节痛,(5)脊柱骨关节炎,(6)

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