METHOD FOR DETERMINING OPTICAL and biophysical parameters of biological tissues AND DEVICE FOR ITS IMPLEMENTATION

摘要

FIELD: medicine.;SUBSTANCE: radiation is supplied onto a tissue into one or more points at wavelengths λ from the range of 350-1600 nm; a diffuse reflection P(L, λ) is measured at wavelengths of the supplied radiations for each lighting point; an absolute R(L, λ) or normalised r(L, λ) spectral-spatial profile of a tissue diffuse reflection coefficient, while the optical and biophysical parameters (X) are determined on the basis of analytic expressions representing multiple regressions between X and R(L, λ) or between X and r(L, λ) produced by measuring or calculating by Monte-Carlo method R(L, λ), r(L, λ) for a number of biotissue samples or control phantoms with the known optical and biophysical parameters; an implementing ensemble of the optical and biophysical parameters of the biotissue and respective spectral-spatial profiles R(L, λ), r(L, λ) for the ranges of the tissue optical and biophysical parameters.;EFFECT: enhancement, higher measurement accuracy of the given parameters of the calibration measurements and use of the prior information.;5 cl, 6 tbl, 7 dwg