首页> 外国专利> METHOD FOR DETECTION OF IMMUNE RECONSTITUTION INFLAMMATORY DISEASE IN PATIENTS WITH DRUG-RESISTANT TUBERCULOSIS AND HIV INFECTION WITH UNDERLYING HIGH-ACTIVE ANTIRETROVIRAL THERAPY

METHOD FOR DETECTION OF IMMUNE RECONSTITUTION INFLAMMATORY DISEASE IN PATIENTS WITH DRUG-RESISTANT TUBERCULOSIS AND HIV INFECTION WITH UNDERLYING HIGH-ACTIVE ANTIRETROVIRAL THERAPY

机译:高效抗病毒治疗后检测抗药性结核和HIV感染患者的免疫重建炎性疾病的方法

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, namely phthisiology and infectious diseases, and may be used for detection of immune reconstitution inflammatory disease in the patients suffering drug-resistant tuberculosis and HIV infection. That is ensured by clinical assessment of the patient's state with underlying high-active antiretroviral therapy (HAART). If observing general loss of condition, temperature rise, progression of inflammatory process in the involved organs, prednisolone 0.5 mg/kg therapy is prescribed once a day for 10-12 days. The therapeutic course of prednisolone is followed by another clinical assessment, and if observing normalised temperature, regression of inflammatory process, general amelioration, the presence of immune reconstitution disease is stated.;EFFECT: use of the given method enables higher accuracy of detection of immune reconstitution disease in the patients with drug-resistant tuberculosis and HIV infection with underlying HAART.;2 ex
机译:技术领域本发明涉及药物,即药理学和传染病,可用于检测抗药性结核病和HIV感染患者的免疫重建炎症性疾病。通过使用潜在的高活性抗逆转录病毒疗法(HAART)对患者状态进行临床评估可以确保这一点。如果观察到疾病的总体丧失,体温升高,受累器官的炎症过程进展,则建议泼尼松龙0.5 mg / kg疗法,每天一次,持续10-12天。泼尼松龙的治疗过程后将进行另一项临床评估,如果观察到正常温度,炎症过程消退,总体改善,则说明存在免疫重建疾病。效果:使用给定方法可以提高免疫检测的准确性具有潜在HAART的耐药性肺结核和HIV感染患者的重组疾病; 2 ex

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