PYRIDYLOXY DERIVATIVES EFFECTIVE AS PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) GAMMA ACTIVATOR/MODULATOR

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: present invention refers to novel pyridyloxy derivatives or its pharmaceutically acceptable ester or a pharmaceutically acceptable salt of the mentioned derivatice or ester of general formula (I), wherein R represents a pyridyl group substituted by 1-3 groups independently specified in a group of substitutes A; the group of substitutes A represents a group comprising halogen atom, C₁-C₆ alkyl group and C₁-C₆ alkoxy group, and Me represents a methyl group. Also, the invention refers to specific compounds of formula (I), to a pharmaceutical composition and a receptor-γ activator/modulator on the basis of a compound of formula (I), to a method of treating and/or preventing a disease.;EFFECT: there are prepared novel pyridyloxy derivatives effective in treating the disease mediated by peroxisome proliferator activated receptor-γ (PPAR) γ.;37 cl, 2 tbl, 21 ex