PREPARATION WITH POLYFUNCTIONAL MEDICAL-BIOLOGICAL ACTIVITY THAT INFLUENCES TISSUE EXCHANGE BASED ON FUNGUS STRAIN Pleurotus ostreatus VKPM F-819

摘要

FIELD: biotechnologies.;SUBSTANCE: preparation with polyfunctional medical-biological activity that influences tissue exchange is produced as a result of liquid-phase depth cultivation of fungus Pleurotus ostreatus All-Russian collection of industrial microorganisms F-819 with further separation of mycelium and cultural liquid and extraction of biologically active substances in the form of a condensed extract from the mycelium. The produced extract, which represents a pharmacological substance of a preparation, is enriched with the agent of the derivative of sterol 4-hydroxy-17P-methylinecisterol with molecular weight of 332.2452 Dalton, polysaccharide β 1-3 glucan and dihydroquercetine with molecular weight of 304.26 Dalton. At the same time the specified components are taken at the following weight ratio: (1):(2):(3):(4) as (79.0-158.0):(1.0-2.0):(10.0-20.0):(10.0-20.0).;EFFECT: invention makes it possible to increase quality of a preparation as a result of increasing its antitumoral activity and reduced toxicity of preparations of antitumoral chemotherapy with simultaneous application with the suggested preparation.;2 cl, 21 dwg, 11 tbl, 2 ex