TRANSPULMONARY LIPOSOME FOR CONTROLLING DRUG DELIVERY

摘要

FIELD: medicine.;SUBSTANCE: there are presented: a liposomal preparation for the pulmonary delivery, wherein the liposomes a surface of which is modified by at least one polymer specified in a group consisting of terminally hydrophobisated polyvinyl alcohols and chitosan, an encapsulated gene, a method for preparing and a method of treating a pulmonary tissue disease involving the stage of administering the above liposomal preparation into the patient's lung. It has been shown that the liposome modified by terminally hydrophobisated polyvinyl alcohol may be kept on the pulmonary tissue surface for a long time.;EFFECT: high effectiveness of the pulmonary delivery of the claimed liposomal preparation for a relatively short time.;10 cl, 1 dwg