BIOCOMPATIBLE BONE-SUBSTITUTING MATERIAL AND METHOD OF OBTAINING THEREOF

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, namely to method of obtaining biocompatible bone-substituting material; powder of biological hydroxyapatite with particle size not more than 40 mcm is obtained from cattle bones, powder of hydroxyapatite is mixed with magnesium phosphate powder with particle size not more than 40 mcm with their ratio 1.0:0.25, water suspension of 2-amino-5-guanidine valeric acid is added to obtained mixture of powders with their further mixing for 40-50 minutes and drying at 50-60°C. Obtained mixture is combined with liquid, containing chitosane solution in 3% water solution of succinic acid and 2% water solution of sodium alginate with their ratio 0.3:0.7, ratio between liquid and powder mixture being 1.0:0.5. Before application hardening agent 5-10% water solution of calcium chloride is added to obtained plastic mass with ratio 1.0:0.3.;EFFECT: obtained material has through pores 0,7-100 mcm, general porosity 50-85%, is biocompatible, biodegradable and contains conditions, which eliminate necessity of t bone tissue transplantation and reoperation.;2 cl, 1 ex