FIELD: medicine, pharmaceutics.;SUBSTANCE: present invention refers to 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one heminapadisylate of formula (I) wherein n is equal to 2, and to pharmaceutically acceptable solvates thereof. Also, the invention refers to a pharmaceutical composition of the salt of formula (I), to a method of treating the above pathological conditions and to using the salt of formula (I) and to the pharmaceutical composition thereof.;EFFECT: what is prepared is the new salt of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one effective in treating the pathological pulmonary conditions, particularly asthma or chronic obstructive pulmonary disease.;11 cl, 3 dwg, 6 ex
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机译:领域:本发明涉及5-(2-{[6-(2,2-二氟-2-苯基乙氧基)己基]氨基} -1-羟乙基)-8-羟基喹啉-2(1H) )-式(I)的一半氨基二甲磺酸酯其中n等于2,并且在药学上可接受的溶剂化物。另外,本发明涉及式(I)的盐的药物组合物,治疗上述病理状况的方法以及使用式(I)的盐及其药物组合物。效果:制备了什么是5-(2-{[6-(2,2-二氟-2-苯基乙氧基)己基]氨基} -1-羟乙基)-8-羟基喹啉-2(1H)的新盐,可有效治疗病理肺部疾病,尤其是哮喘或慢性阻塞性肺疾病。; 11 cl,3 dwg,6 ex
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