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A method for the production of nano - dispersed high - all - trans - carotenoid - microcapsules

机译:一种纳米分散高全反式类胡萝卜素微囊的生产方法。

摘要

The present invention discloses a process for the preparation of nano - dispersed high - all - trans - carotenoid - microcapsules, in which high - all - trans - carotenoid - crystals, together with dichloromethane, by knives to a crystal size of 2 – 5 μm are ground up, in order to provide a 10 – 20% - carotenoid - suspension liquid preparing. The relevant suspension liquid, in a different route is preheated dichloromethane in a solution reactor and to a 0,5 – 2% - solvent liquid is released. The above-mentioned solvent with alcohol or isopropanol is simultaneously and continuously over a difficult to force - crystal deposition in front of the direction with a rotating fixed bed and subsequently fed in a thin film evaporator, up to a solids content of 10 – 20% released from solution. In this way, a transparent carotenoid - alcohol - dispersion liquid obtain. The corresponding alcohol - dispersion liquid is water solution containing antioxidant, and protective colloid are mixed, and dried atomized. In this way, nano - dispersed high - all - trans - carotenoid - microcapsules obtained. Because the nano - dispersed high - all - trans - carotenoid - microcapsules crystals contained nano - are dispersed and the content of trans - isomers of over 90%, the biological availability is extremely high.
机译:本发明公开了一种制备纳米分散的高-全-反-类胡萝卜素-微胶囊的方法,其中高-全-反-类胡萝卜素-晶体与二氯甲烷一起用小刀切成晶体尺寸为2-5μm。进行研磨,以提供10 – 20%的类胡萝卜素悬浮液。在不同的途径中,将相关的悬浮液在溶液反应器中预热二氯甲烷,并释放出0.5-2%的溶剂液。上面提到的含酒精或异丙醇的溶剂在难以强制的情况下同时连续进行-用旋转的固定床在方向前方沉积晶体,然后将其送入薄膜蒸发器中,固含量最高为10 – 20%从解决方案中释放。这样,得到透明的类胡萝卜素-醇-分散液。相应的醇-分散液是含有抗氧化剂的水溶液,将保护胶体混合并干燥雾化。以此方式,获得了纳米分散的高-全-反-类胡萝卜素-微胶囊。由于纳米分散的高-全-反-类胡萝卜素-纳米微胶囊晶体被分散并且反式异构体的含量超过90%,因此生物学利用率非常高。

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