Increase in the lipid content in microalgae by genetic manipulation of a triacylglycerol (day) - lipase

摘要

The present invention relates to a process for the increase in the lipid content in an organism, in particular a microalgae by means of the modulation of the activity of a triacylglycerol (day) lipase. The present invention furthermore relates to the organisms obtained by this method, or microalgae, with increased lipid content, as well as their applications in industry and medicine, in particular for the recovery of omega - 3 - unsaturated fatty acids. The invention is concerned, in addition, with a nucleic acid from phaeodactylum tricornutum, which codes for a new day lipase, as well as their use in the influencing of the proportion of fatty acids, in particular of the content of polyunsaturated fatty acids in biomasses.