Romer by weight, the detector and the method for the determination of the radiation exposure by means of chromosome abnormalities

摘要

The invention relates to a method for determining radiation exposure by means of chromosomes abnormalities in a sample, by determining the position or the locations of the centromere each chromosome in a cell in an image of a meta phases cell by segmenting an exactly drawn chromosomes means line with subsequent selection of a longitudinal cross section with a minimal width or intensity or the width and intensity, by determining the number of centromeric in each chromosome in each cell, by calculating the frequency dicentric chromosomes in a cell population; and by determining the radiation dose by comparing the determined frequency dicentric chromosomes with a previously defined dose - action curve from a calibrated source.