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DNA aptamer that specifically binds to pLDH, malaria diagnostic composition, and malaria diagnostic kit

机译:与pLDH,疟疾诊断成分和疟疾诊断试剂盒特异性结合的DNA适体

摘要

Disclosed herein are a DNA aptamer specifically binding to pLDH (Plasmodium Lactate Dehydrogenase), a composition for the diagnosis of malaria, comprising the same, and a diagnostic kit for malaria using the same. Superior in specificity and stability to antibodies which are conventionally used to diagnose malaria, the DNA aptamers specifically binding to pLDH (Plasmodium Lactate Dehydrogenase) in accordance with the present invention can be developed into biosensors which determine pLDH levels with high sensitivity and accuracy, greatly contributing to the diagnostic accuracy of malaria.
机译:本文公开了与pLDH(乳酸疟原虫脱氢酶)特异性结合的DNA适体,用于诊断疟疾的组合物,包括其的疟原虫和用于诊断疟疾的试剂盒。与常规用于诊断疟疾的抗体相比,其特异性和稳定性优越,可以将根据本发明与pLDH(乳酸疟原虫脱氢酶)特异性结合的DNA适体开发成生物传感器,以高灵敏度和准确度确定pLDH的水平,这在很大程度上有助于对疟疾的诊断准确性。

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