Condensed aromatic difluoromethane phosphonates as protein tyrosine phosphatase 1B (PTP-1B) inhibitors

摘要

The invention encompasses the novel class of compounds represented by the formula below, which are inhibitors of the PTP-1B enzyme. The invention also encompasses pharmaceutical compositions which include the compounds shown (Formula I) above and methods of treating or preventing PTP-1B mediated diseases, including diabetes.