Process for the preparation of secondary amides by carbonylation of corresponding tertiary amines

摘要

The presence of a halogen-containing promoter and the presence of a metal catalyst, by the carbonylation with carbon monoxide and tertiary amine corresponding in the reaction mixture, the invention produce secondary amides under good selectivity on how to. Metal catalyst comprises palladium. By palladium, when the palladium is used in low concentrations in particular, the same as or rhodium much more expensive, catalytic activity much better can be obtained. In addition, I can also be achieved good selectivity.