FIBROBLAST MOBILIZING AGENT AND WOUND REMEDY AGENT CONTAINING G-CSF

摘要

PROBLEM TO BE SOLVED: To provide a wound remedy agent easily mobilizing fibroblasts toward a wound tissue without fibroblast transplantation, and engrafting the fibroblasts in the wound tissue.SOLUTION: A fibroblast mobilizing agent includes a granulocyte colony-stimulating factor (G-CSF) as an active ingredient. The fibroblast mobilizing agent mobilizes fibroblasts to a wound tissue. The fibroblasts are mobilized to a heart. The heart is a heart after the onset of heart disease. The heart disease is myocardial infarction. By administering G-CSF, fibroblasts are transferred into a myocardial infarction lesion. Thus, deterioration of heart function is prevented and cardiac remodeling is improved.