Tertiary formamides purification contaminated tertiary acetamide

摘要

Is used to neutralize or remove the tertiary acetamide is present as a contaminant in the tertiary formamide solvent, a chlorinating agent chloro iminium species like. It can be used as the reaction medium for chlorination of sucrose-6-acylate, the tertiary formamide solvent treated or purified in this manner, (intermediates in the preparation of sucralose) sucralose-6-acylate desired thereby yield can be improved. None [Selection Figure]