2,3 Dihydro-1H-inden-1-yl-2,7-diazaspiro 3.5 nonane derivatives and their use as antagonists or inverse agonists of the ghrelin receptor

摘要

The present invention provides a compound of Formula (I) or a pharmaceutically salt thereof wherein R1, R2, Ra, L, Z, Z1 and Z2 are as defined herein, that act as Ghrelin antagonists or inverse agonists; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by the antagonism of the Ghrelin receptor.