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Target-specific gene delivery for immunization of dendritic cells
Target-specific gene delivery for immunization of dendritic cells
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机译:用于树突细胞免疫的靶标特异性基因递送
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摘要
Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific targeting molecule. The methods and related compositions can be used to treat patients suffering from a wide range of conditions, including infection, such as HIV/AIDS, and various types of cancers.
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