首页> 外国专利> Amorphous form of heterocyclic compound, solid dispersion containing the same, drug, and method for producing the same

Amorphous form of heterocyclic compound, solid dispersion containing the same, drug, and method for producing the same

机译:杂环化合物的无定形形式,包含其的固体分散体,药物及其制备方法

摘要

[PROBLEMS] The object is to improve the absorbability of a heterocyclic compound including s-triazine and a pyrimidine derivative in vitro. [MEANS FOR SOLVING PROBLEMS] Disclosed is, for example, an amorphous body of a heterocyclic compound as represented by the general formula (I) [wherein each of R's and others is as defined in the description] including s-triazine and a pyrimidine derivative, or a hydrate, a solvate or a pharmaceutically acceptable salt of the heterocyclic compound. Also disclosed is a process for producing the amorphous body Further disclosed are: a solid dispersion comprising the amorphous body; and a medicinal preparation comprising the solid dispersion.
机译:[问题]目的是提高包含s-三嗪和嘧啶衍生物的杂环化合物的体外吸收性。 [解决问题的方法]公开了例如由通式(I)表示的杂环化合物的无定形体,其中R和其他均如说明书中所定义,包括s-三嗪和嘧啶衍生物。或杂环化合物的水合物,溶剂化物或药学上可接受的盐。还公开了一种制备无定形体的方法。以及包含所述固体分散体的药物制剂。

著录项

  • 公开/公告号JP5479912B2

    专利类型

  • 公开/公告日2014-04-23

    原文格式PDF

  • 申请/专利权人 全薬工業株式会社;

    申请/专利号JP20090542608

  • 申请日2008-11-21

  • 分类号A61K31/5377;A61K47/38;A61P1/04;A61P1/06;A61P1/18;A61P11;A61P11/02;A61P11/06;A61P13/12;A61P17;A61P17/04;A61P17/06;A61P19/02;A61P19/08;A61P27;A61P27/02;A61P29;A61P31/04;A61P35;A61P35/02;A61P37;A61P37/02;A61P37/08;C07D403/04;

  • 国家 JP

  • 入库时间 2022-08-21 16:12:17

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