Culturing NK cell activated method, NK cell multiplication method and cell production method and include the NK cell the single nuclear sphere null lymph node

摘要

PPROBLEM TO BE SOLVED: To provide a method for activating NK cells by which the NK cells having non-specific cytotoxic activity to various tumor cells, virus-infected cells and the like, or ADCC activity can be activated to safely and simply proliferate without mixing with K562 or the like; a method for proliferating and producing the NK cells using the same; and monocytes containing a large amount of the NK cells. PSOLUTION: In the method for activating the NK cells, the Nk cells are activated by stimulating the monocytes containing T cells and NK cells with a CD52 agonist. The stimulation of the monocytes with the CD52 agonist is carried out in the presence of a cytokine. PCOPYRIGHT: (C)2011,JPO&INPIT