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Preventive or therapeutic agent for neuropathic pain associated with Guillain-Barre syndrome

机译:格林-巴利综合征相关的神经性疼痛的预防或治疗剂

摘要

A P2X4 receptor antagonist such as paroxetine or a diazepinedione derivative represented by the following general formula (IX) is used as a preventive or therapeutic agent for neuropathic pain associated with Guillain-Barre syndrome. (Wherein R1 represents a hydrogen atom, an alkyl group having 1 to 8 carbon atoms, R2 and R3 represent a hydrogen atom, an alkyl group having 1 to 8 carbon atoms, etc., R4 and R5 represent a hydrogen atom and the like, W represents a 5- or 6-membered heterocyclic ring containing 1 to 4 nitrogen atoms as a ring constituent element which may have a substituent.
机译:由以下通式(IX)表示的P2X4受体拮抗剂例如帕罗西汀或二氮杂二酮衍生物被用作与格林-巴利综合征相关的神经性疼痛的预防剂或治疗剂。 (其中R1代表氢原子,具有1至8个碳原子的烷基,R2和R3代表氢原子,具有1至8个碳原子的烷基,等等,R4和R5代表氢原子等, W表示含有1-4个氮原子作为可具有取代基的环组成元素的5或6元杂环。

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