首页> 外国专利> OPTIMIZING MIFEPRISTONE LEVELS IN PLASMA SERUM OF PATIENTS SUFFERING FROM MENTAL DISORDERS TREATABLE WITH GLUCOCORTICOID RECEPTOR ANTAGONISTS

OPTIMIZING MIFEPRISTONE LEVELS IN PLASMA SERUM OF PATIENTS SUFFERING FROM MENTAL DISORDERS TREATABLE WITH GLUCOCORTICOID RECEPTOR ANTAGONISTS

机译:糖皮质激素受体拮抗剂可治疗精神错乱患者血浆中米非司酮水平的优化

摘要

The present invention provides a method for optimizing levels of mifepristone in a patient suffering from a mental disorder amenable to treatment by mifepristone. The method comprises the steps of treating the patient with seven or more daily doses of mifepristone over a period of seven or more days; testing the serum levels of the patient to determine whether the blood levels of mifepristone are greater than 1300 ng/mL; and adjusting the daily dose of the patient to achieve mifepristone blood levels greater than 1300 ng/mL.
机译:本发明提供了一种在患有可通过米非司酮治疗的精神疾病的患者中优化米非司酮水平的方法。该方法包括以下步骤:在七天或更长时间的时间内,每天服用七次或更多次米非司酮治疗患者;检测患者的血清水平,以确定米非司酮的血液水平是否大于1300 ng / mL;并调整患者的每日剂量以使米非司酮的血药浓度高于1300 ng / mL。

著录项

  • 公开/公告号US2014162993A1

    专利类型

  • 公开/公告日2014-06-12

    原文格式PDF

  • 申请/专利权人 CORCEPT THERAPEUTICS;

    申请/专利号US201314065792

  • 发明设计人 JOSEPH K. BELANOFF;

    申请日2013-10-29

  • 分类号G01N33/49;A61K31/575;

  • 国家 US

  • 入库时间 2022-08-21 16:09:50

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