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Combining RNAi Imaging Data With Genomic Data For Gene Interaction Network Construction

机译:将RNAi成像数据与基因组数据相结合以构建基因相互作用网络

摘要

Embodiments of the invention relate to a method, system, and computer program product to construct a gene interaction network by combining two sources of genomic information, namely RNAi imaging data and gene expression data. Tools are provided to gather data, including gene expression data and gene image data, and to compute measurements and relationships, respectively. A graph is constructed with nodes representing genes and edges drawn between the nodes to form gene clusters. The graph is refined such that the shape captures a structural pattern of the cluster.
机译:本发明的实施例涉及通过组合两个基因组信息源即RNAi成像数据和基因表达数据来构建基因相互作用网络的方法,系统和计算机程序产品。提供了工具来收集数据,包括基因表达数据和基因图像数据,以及分别计算测量值和关系。构造一个图,其中包含代表基因的节点,并在节点之间绘制边缘以形成基因簇。精简图形,以使形状捕获群集的结构模式。

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