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Non Human Animal Models for Increased Retinal Vascular Permeability
Non Human Animal Models for Increased Retinal Vascular Permeability
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机译:非人类动物模型增加视网膜血管通透性
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摘要
The present invention relates to a non human animal model for increased retinal vascular permeability wherein said increased retinal vascular permeability is induced by inhibiting in Müller cells of said animal the expression of a gene encoding for Dp71 or a dystrophin associated protein (DAP). Furthermore, the present invention relates to methods and compositions for the treatment of a disease associated with an increased retinal vascular permeability in a subject in need thereof.
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