首页> 外国专利> APPLICATION OF COMPOSITION CONTAINING TELECHELIC MACROMER AND PHOTOINITIATOR FOR PRODUCING IMPLANT FOR HERNIA REPAIR

APPLICATION OF COMPOSITION CONTAINING TELECHELIC MACROMER AND PHOTOINITIATOR FOR PRODUCING IMPLANT FOR HERNIA REPAIR

机译:包含远距离微距和光引发剂的组合物在疝修补剂生产中的应用

摘要

The present invention relates to an application of a composition containing telechelic macromer and photoinitiator for producing implant for hernia repair. The macromer structure is defined by Formula 1. The macromer bears (meth)acrylic end-groups and comprises a core Y defined by Formulas 2 to 9, that is linked by urethane, ester or anhydride bonds to the (meth)acrylic groups. The iodine value of the macromer is from 5 to 75. The composition according to the present invention can be shaped at room temperature and at 37° C. and is capable of undergoing liquid-to-solid transition upon irradiation with low intensity light. Upon irradiation with light the composition gains desired physicochemical properties and turns into an elastic solid. The implant for hernia repair serves for closing the hernia opening and for enhancing mechanical strength of abdominal wall.
机译:本发明涉及包含远螯大分子单体和光引发剂的组合物在制备用于疝气修复的植入物中的应用。大分子单体结构由式1定义。大分子单体带有(甲基)丙烯酸端基并且包含由式2至9定义的核Y,其通过氨基甲酸酯,酯或酸酐键连接至(甲基)丙烯酸基团。大分子单体的碘值为5至75。根据本发明的组合物可以在室温和37℃下成形,并且在用低强度光照射时能够经历液-固转变。在光照射下,组合物获得所需的物理化学性质并变成弹性固体。用于疝气修复的植入物用于闭合疝气开口并增强腹壁的机械强度。

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