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REGULATORS OF NFAT AND/OR STORE-OPERATED CALCIUM ENTRY
REGULATORS OF NFAT AND/OR STORE-OPERATED CALCIUM ENTRY
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机译:NFAT和/或商店操作的钙进入的调节剂
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摘要
Embodiments of the inventions relate to modulating NFAT activity, modulating store-operated Ca2+ entry into a cell and treating and/or preventing hyperactivity or inappropriate immune response by inhibiting the expression or activities of septin 4 (SEPT 4) and septin 5 (SEPT 5) proteins involved in the calcineurin/NFAT axis and T-cell activation.
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