首页> 外国专利> APPARATUS AND METHOD PERTAINING TO DETERMINING A SPATIALLY-VARIANT NORMAL TISSUE CONSTRAINT AS A FUNCTION OF DOSE DISTRIBUTION

APPARATUS AND METHOD PERTAINING TO DETERMINING A SPATIALLY-VARIANT NORMAL TISSUE CONSTRAINT AS A FUNCTION OF DOSE DISTRIBUTION

机译:确定空间变异的正常组织约束作为剂量分布函数的装置和方法

摘要

A control circuit optimizes a radiation-treatment plan (as regards treating at least one target volume for a given patient) by automatically determining a spatially-variant normal tissue constraint as a function, at least in part, of dose distribution for normal tissue that is proximal to the target volume. If desired, the control circuit can repeatedly determine spatially-variant normal tissue constraints while optimizing the radiation-treatment plan. This automatic determination can comprise evaluating dose distributions at specific different distances from the target volume. So configured, the control circuit can effect such evaluation by penalizing, during the optimization of the radiation-treatment plan, dose distribution levels that exceed a predetermined distribution property (such as an aggregation value for the dose values including, but not limited to, an average value of dose values for each of the given specific different distances) at a given one of the specific different distances.
机译:控制电路通过自动确定空间变化的正常组织约束(至少部分地取决于正常组织的剂量分布的函数)来优化放射线治疗计划(就给定患者的至少一个目标体积而言)。接近目标体积。如果需要,控制电路可以在优化放射治疗计划的同时重复确定空间变化的正常组织约束。该自动确定可以包括评估距目标体积特定不同距离处的剂量分布。如此配置,控制电路可以通过在放射治疗计划的优化期间惩罚超过预定分布特性的剂量分布水平(例如,包括但不限于剂量的剂量值的聚合值)来进行这种评估。在给定的一个特定的不同距离处,每个给定的特定的不同距离的剂量值的平均值)。

著录项

  • 公开/公告号US2014018602A1

    专利类型

  • 公开/公告日2014-01-16

    原文格式PDF

  • 申请/专利权人 JANNE NORD;JARKKO PELTOLA;

    申请/专利号US201213548590

  • 发明设计人 JANNE NORD;JARKKO PELTOLA;

    申请日2012-07-13

  • 分类号A61N5/10;

  • 国家 US

  • 入库时间 2022-08-21 16:05:31

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