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Conjugate addition reactions using bifunctional Cinchona-alkaloid-based catalysts
Conjugate addition reactions using bifunctional Cinchona-alkaloid-based catalysts
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机译:使用双功能 Cinchona I>-生物碱基催化剂进行加成反应
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摘要
One aspect of the present invention relates to quinine-based and quinidine-based catalysts. Another aspect of the present invention relates to a method of preparing a chiral, non-racemic compound from a prochiral electron-deficient alkene, comprising the step of: reacting a prochiral electron-deficient alkene with a nucleophile in the presence of a catalyst; thereby producing a chiral, non-racemic compound; wherein said catalyst is a derivatized quinine or quinidine.
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