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Methods and Compositions for Unsilencing Imprinted Genes
Methods and Compositions for Unsilencing Imprinted Genes
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机译:沉默印迹基因的方法和组成
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摘要
The present invention provides methods and compositions for inducing expression of Ube3a in a cell by contacting the cell with a topoisomerase inhibitor. Particular embodiments include a method of treating a genomic imprinting disorder, such as Angelman syndrome, in a subject by administering to the subject an effective amount of a topoisomerase inhibitor.
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