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Use of toll-like receptor ligands as adjuvants to vaccination therapy for brain tumors
Use of toll-like receptor ligands as adjuvants to vaccination therapy for brain tumors
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机译:Toll样受体配体作为佐剂在脑肿瘤疫苗接种治疗中的应用
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摘要
Compositions comprising dendritic cells pulsed with tumor lysate and at least one toll-like receptor (TLR) ligand which may be used for eliciting a specific immune response in a mammal in need thereof for treating diseases including a tumor are disclosed. Also disclose are methods of activating dendritic cells, comprising providing at least one toll-like receptor (TLR) ligand; and pulsing a dendentic cell with the at least one TLR ligand. A method further comprises pulsing the dendritic cell with a tumor lysate.
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