首页> 外国专利> REPEAT-CHAIN FOR THE PRODUCTION OF DIMER, MULTIMER, MULTIMER COMPLEX AND SUPER-COMPLEX

REPEAT-CHAIN FOR THE PRODUCTION OF DIMER, MULTIMER, MULTIMER COMPLEX AND SUPER-COMPLEX

机译:重复链,用于生产二聚体,多聚体,多聚体复合物和超复杂性

摘要

The present invention relates to a method for manufacturing multimers by making repeat-chains comprising repeatedly linked affinity domains binding specifically to monomers, and by using the same to create a repeat-chain/multiple-monomer complex created from the repeat-chains and a multiple number of monomers, thereby facilitating the formation of bond bridges between the monomers in the complex to produce inter-monomeric bond bridged multimer.;The present invention relates to a super-complex prepared by cross-binding between repeat-chain/multiple-monomer complexes, and a method for amplifying the effect of monomer through the formation of the said super-complex. Particularly, the repeat-chain/multiple-monomer complex is prepared by containing repeat-chains of binding domain having binding specificity to monomers as active ingredients, and then the super-complex is prepared by cross-binding between such complexes.
机译:本发明涉及一种用于制造多聚体的方法,该方法是通过制备包含与单体特异性结合的重复连接的亲和结构域的重复链,并通过使用该重复链产生由重复链和多个数量的单体,从而促进复合物中单体之间的键桥的形成,以产生单体间键桥联的多聚体。本发明涉及通过重复链/多单体复合物之间的交联制备的超复合物。以及通过形成所述超配合物来增强单体作用的方法。特别地,通过包含对单体具有结合特异性的结合结构域的重复链作为活性成分来制备重复链/多单体复合物,然后通过在这些复合物之间进行交叉结合来制备超复合物。

著录项

  • 公开/公告号US2013323717A1

    专利类型

  • 公开/公告日2013-12-05

    原文格式PDF

  • 申请/专利权人 MUHYEON CHOE;

    申请/专利号US201313904824

  • 发明设计人 MUHYEON CHOE;YONGCHAN LEE;JAESEON WON;

    申请日2013-05-29

  • 分类号C07K16;C07K14/315;

  • 国家 US

  • 入库时间 2022-08-21 16:03:15

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