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METHODS AND COMPOSITIONS TO ELIMINATE CHRONIC LYMPHOCYTIC LEUKEMIA AND OTHER HEMATOLOGIC MALIGNANT CELLS IN STROMAL MICROENVIRONMENT FOR CANCER THERAPY
METHODS AND COMPOSITIONS TO ELIMINATE CHRONIC LYMPHOCYTIC LEUKEMIA AND OTHER HEMATOLOGIC MALIGNANT CELLS IN STROMAL MICROENVIRONMENT FOR CANCER THERAPY
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机译:消除基质微环境中慢性淋巴细胞白血病和其他造血性恶性肿瘤细胞的方法和组合物
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摘要
The present invention regards compositions and methods for treating chronic lymphocytic leukemia in the in vivo tissue environment using selenium-containing compositions. In particular aspects, a selenium-comprising compound is administered to an individual wherein the CLL cells are in a stromal cell environment, wherein stromal factors modulate the selenium comprising compound to enhance its activity.
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