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Tympanic membrane permeating ear drops and uses thereof
Tympanic membrane permeating ear drops and uses thereof
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机译:鼓膜渗透滴耳剂及其用途
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摘要
The present invention provides compositions and methods for noninvasive delivery of therapeutic agents across an intact tympanic membrane. For example, the compositions include a penetration enhancer which increases the flux of a therapeutic agent (e.g., antibiotic) across the tympanic membrane. Such compositions are particularly useful in the treatment of otitis media. Additionally, the composition may include a sustained release agents that, in some embodiments form sustained release reservoirs, in situ, once administered to a patient.
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